Macdonald Lab

Wilson, J. and Macdonald, P.M. (1993).

Formation of the germ line in Drosophila.

Current Opinion in Genetics and Developmental Biology 3, 562-565.

Abstract

In Drosophila, germ cell formation is directed by the posterior pole plasm of the embryo. Genes acting to provide the germ cell determinant have been identified and characterized, and some are now being manipulated to test their roles. Although recent results largely support the notion of a simple pathway for assembly of pole plasm, complexities are becoming apparent.